Skin Issues Of Cancer Patients
Monday, March 31st, 2008Cancer patients’ skin issues broke out with the emergence of a hefty new class of chemotherapy drugs. These agents affect specific proteins in cancer cells other than the “spray gun approach” of established chemotherapy that “basically shoots at all things and kills all types of cells,”. The new agents derogate the side effects of conventional chemotherapy so people lose less hair and don’t suffer from plumping white blood cell counts, which leave them compromising to infections.
The new drugs function by destroying a protein named the EGFR, which naturally happens in the skin, but also assists cancer cells thrive. In the top four deathliest cancers — breast, lung, pancreatic and colorectal — cancer cells start moiling out huge amounts of EGFR to feast themselves and self circulate. The drugs that affect EGFR are given to patients — around 100,00 so far — whose cancer has not reacted to traditional chemotherapy.
But EGFR, which the medicines so handily wipe out, also is decisive for the normal operation of skin. Thus, around 90 percent of patients who take it have skin issues so serious that they feel discomfited by their appearance. Every patient responds differently to dermatological management. Lacouture is examining the outcomes of 150 of his patients to decide the most effective interferences for the acne rash. He also is studying the effectiveness of newer medicines against acne rash in a new research.